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KMID : 0371620020170010055
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Journal of Wonkwang Medical Science
2002 Volume.17 No. 1 p.55 ~ p.64
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Restenosis Rate and Predictive Factors of Restenosis After Percutaneous Coronary Intervention in the Patients with Coronary Artery Disease
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Oh Seok-Kyu
Kim Nam-Ho
Yoo Nam-Jin
Yun Kyeong-Ho
Ahn Seon-Ho
Park Byoung-Hyun
Lee Myeung-Su
Shim Hyeok
Rhee Sang-Jae
Kim Jae-Kwon
Lee Dong-Soo
Bae Eun-Chul
Park Yang-Kyu
Jeong Jin-Won
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Abstract
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Background : Restenosis remains one of major clinical problems in percutaneous coronary intervention(PCI). The objective of this study was to identify the restenosis rate after PCI and to identify clinical and angiographic factors that can predict restenosis after coronary stent placement.
Methods : One hundred and ten treated lesions of 84 patients(59±10 year-old, 62 male), who underwent PCI and follow-up angiography in the Wonkang University Hospital from October 2000 to December 2001, was included. Follow-up angiography was performed at average 8.7 months(2∼22 months) after PCI. Angiographic restenosis was defined as a stenosis of over 50% diameter at follow-up coronary angiography. Clinical variables, risk factors, angiographic characteristics, and restenosis rate of the stenting group(87 lesions) were compared with that of the PTCA group(23 lesions). In the stenting group, the clinical and angiographic factors associated with restenosis after PCI was analyzed.
Results : The clinical diagnosis of the subjects were myocardial infarction in 51 patients, unstable angina in 28, and stable angina in 5. The overall restenosis rate was 23.6%(26/110 lesions). The restenosis rate was 23.0%(20/87 lesions) after stent placement and 26.0%(6/23 lesions) after PTCA(p=0.756). In the stenting group, diabetes(p=0.033), lesion type(p=0.021), modified lesion type(0.004), and total occlusion(0.017) were associated with restenosis after stent placement, but other factors were not associated.
Conclusion : Coronary stent placement results in a lower rate of restenosis in the treatment of the patient with coronary artery disease. Diabetes, lesion type, modified lesion type and total occlusion are significant predictors of restenosis after coronary stent placement.
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KEYWORD
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Coronary artery disease, Stent, PTCA, Restenosis
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